woensdag 4 februari 2009

High-throughput analysis unravels secrets of GI tract microbiota

A review article in Gut describes recent developments in analyzing the vast diversity of microbiota that inhabit our gastrointestinal (GI) tract. The authors argue that high-throughput technologies are indispensable to further identify GI micro-organisms and their role in health and disease.

Trillions of bacteria inhabit the human gut. It is estimated that they outnumber our human body cells by a factor of ten. The majority of these microbes are yet unknown. An estimated 50 to 90% of them cannot be cultured by microbiological techniques. This makes it difficult to identify them, let alone to formulate hypotheses about their role in health and disease.
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