donderdag 19 februari 2009

Probiotics-induced changes in the intestine

Probiotics activate certain genes in the intestinal wall, according to a recent study by Wageningen University. Most of these genes are involved in the immune response of healthy adults. The results represent the first molecular evidence of the effect of probiotics. Lead researcher Michiel Kleerebezem: "The pattern was very clear."

It was no news that probiotics can influence certain immune parameters. How that influence is effectuated at the molecular level, however, was still unknown. A study by the Top Institute Food and Nutrition (TIFN) now shows that living cells of Lactobacillus plantarum activate certain genes in the intestinal wall. These genes play an important role in the immune response of healthy adults. The results appeared in PNAS Online (February 4th).
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