maandag 21 september 2009

LGG successful thanks to hair-like structures

The probiotic strain LGG, present in a popular yoghurt drink, is a champion in sticking to our intestinal mucus. An international research team has found a plausible explanation for this essential characteristic.

Genetically, Lactobacillus rhamnosus GG (LGG) hardly differs from its close relative L. rhamnosus LC705. Functionally, however, there is one major difference: LGG has probiotic properties, whereas LC705 does not. A team of Finnish, Belgian and Dutch scientists decided to find out why that is, and found a very promising clue: LGG has tiny hair-like structures on its cell surface that allow it to bind to the human intestinal mucus layer. The team published their results in the Proceedings of the National Academy of Sciences (PNAS, online on Sept. 17).
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